Oxathiaphospholane
http://www.chem.ucla.edu/~harding/IGOC/O/oxaphosphetane.html WebAug 4, 2005 · 5‘-O-DMT-deoxyribonucleoside-3‘-O-(2-selena-4,4-pentamethylene-1,3,2-oxathiaphospholane) monomers, derivatives of dA, dC, dG, and T, can be resolved into pure P-diastereomers by silica gel column chromatography. They have been used for DBU-promoted, either solution- or solid-phase synthesis of P-stereodefined …
Oxathiaphospholane
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Web免疫刺激核酸专利检索，免疫刺激核酸属于·碳水化合物糖其衍生物专利检索，找专利汇即可免费查询专利，·碳水化合物糖其衍生物专利汇是一家知识产权数据服务商，提供专利分析，专利查询，专利检索等数据服务功能。 WebJan 1, 2001 · For oxathiaphospholane rings in the solid state, both envelope and half-chair conformations, differently distorted, are observed. In oxathiaphospholane rings with the envelope conformation, the endocyclic carbon atom next to the ring oxygen atom is …
WebApr 1, 2012 · The reactions of 17α-hydroxyprogesterone with Lawesson’s reagent (LR) in toluene, CH 2 Cl 2 and/or CCl 4 gave, depending on the duration of the reaction, two diastereoisomeric androst-4-en-17-spiro-1,3,2-oxathiaphospholane-2-sulfide pairs 2a,b and 3a,b in approximately 7:3 ratio, differing in configuration at the phosphorus atom. A … WebJan 1, 2001 · For oxathiaphospholane rings in the solid state, both envelope and half-chair conformations, differently distorted, are observed. In oxathiaphospholane rings with the envelope conformation, the endocyclic carbon atom next to the ring oxygen atom is in the flap position. For dithiaphospholane compounds, the heterocyclic rings prefer a half-chair ...
WebApr 12, 2005 · Two polymers bound to N,N-diisopropylamino-1,3,2-oxathiaphospholane were reacted with unprotected carbohydrates and nucleosides in the presence of 1H-tetrazole, followed by oxidation with tert-butyl hydroperoxide or sulfurization with Beaucage's reagent. The 1,3,2-oxathiaphospholane ring-opening with 3-hydroxypropionitrile, followed by … WebJan 1, 2001 · In this paper, the geometry and conformation of oxathiaphospholane and dithiaphospholane rings in the solid state are described on the basis of our re…
Web1 Synthesis of PS/PO-Chimeric Oligonucleotides Using Mixed Oxathiaphospholane and Phosphoramidite Chemistry Ewa Radzikowskaa, and Janina Baraniaka,b* aDepartment of Bioorganic Chemistry, Center of Molecular and Macromolecular Studies, Polish Academy of Sciences, Sienkiewicza 112, 90-363 Łódź, Poland bInstitute of Chemistry, Environmental …
WebApr 23, 2001 · In conclusion, the results presented in this paper provide the evidence that oxathiaphospholane methodology can be successfully applied for the stereocontrolled synthesis of LNA dinucleoside phosphorothioates in solution. Further studies on the adaptation of this approach to the requirements of solid-phase oligonucleotide synthesis … mobil on the run car wash promotionsWebSynthesis of oxathiaphospholane monomers 2 and 3 – a general procedure Oxathiaphospholane monomers 2 and 3 were synthesized analogously to a general procedure published for the synthesis of standard OTP monomers.34 Brie y, a suitable nucleoside 4 (2 mmol, N-protected if necessary; Scheme 1) was dried over- mobilon networksWeb(a) R 1, R 3, R 5 and R 6 are independently hydrogen, CD 3 or CF 3, linear or branched C 1-C 20 alkyl, optionally substituted with one or more, the same or different, R a groups; ink tank printer comparisonmobil on the run employmentWebJan 30, 2001 · Oxathiaphospholane Approach to the Synthesis of P-Chiral, Isotopomeric Deoxy(ribonucleoside phosphorothioate)s and Phosphates Labeled with an Oxygen Isotope Piotr Guga Dr. , Centre of Molecular and Macromolecular Studies Polish Academy of Sciences Department of Bioorganic Chemistry Sienkiewicza 112, 90-363 Łódź, Poland, … ink tank tattoo redmond oregonWebMay 24, 2004 · A 1,3,2-oxathiaphospholane ring-opening condensation method was also used for the synthesis of mixed backbone phosphate/phosphorothioate 2 oligonucleotides and [ 18 O]-labelled isotopomeric oligonucleotides. 3 Condensation of 5′- O -DMT-thymidine 3′- O - (2-seleno-1,3,2-oxathiaphospholane) with 3′- O -acetylthymidine in the presence of … mobil online s.r.oWebSep 14, 2004 · This oxathiaphospholane approach ensures the availability of nucleoside 5‘- Pα -boranodiphosphate analogues needed for antiviral drug research. Supporting Information Available 1 H NMR and 31 P NMR spectra for each diastereomer of compounds 5a − d and the corresponding HPLC profiles. ink tank printer with document feeder